Brian N. Brogle, MD; Thanjuvar S. Ravikumar, MD; Mihye Choi, MD; Kenneth B. Cummings, MD Soft tissue sarcomas of the testis, spermatic cord, inguinal region or perineum are rare and difficult to manage. We describe the principles and techniques of pelvic exenteration with en bloc resection of the perineum and genitalia for treatment of recurrent sarcoma of the perineum.