Introduction: Duodenal diverticula are most common in second part of duodenum at level of ampulla. The diverticula of the third part of the duodenum are rare.

Methods: This is a case of an 80-year old male who presented with vague epigastric pain and history of Barret's esophagus. He was diagnosed with duodenal diverticulum on upper GI endoscopy, and scheduled for elective laparoscopic resection.

Results: After accessing the abdominal cavity, the infra and supramesocolic areas were accessed. The ligament of Treitz was released and the duodenum was derotated. Meticulous mobilization from adhesions was done. After mobilization and elevation the diverticulum was resected with a 60mm linear stapler. The staple line was oversewn with a running vicryl suture. The patient tolerated the procedure well with minimal blood loss. Postoperative upper GI studies were normal and patient was started on normal diet.

Conclusion: Laparoscopic resection of a third portion of the duodenum diverticulum is safe and feasible.