The patient is a 62 year old woman with a six year history of left sided abdominal and back pain. CT scan of the abdomen showed a 3.5 cm solid, heterogenous, lobular mass in the body of the pancreas. There was no evidence of metastatic disease. CEA and CA 19-9 were normal. Central pancreatectomy was recommended because of concern about the malignant potential of this lesion and the patient's history of diet-controlled diabetes. The abdomen was explored through an upper midline incision. A Kocher maneuver was performed and the gastrocolic omentum opened. After confirming the location of the tumor with palpation and intraoperative ultrasound, the neck of the pancreas was stapled with a TA-60, divided, and the pancreatic duct oversewn. Uniform apposition of the pancreatic capsule along the staple line was verified. The body of the pancreas was mobilized off of the splenic artery and vein for a a distance of about 6 cm. This distance allowed resection of the tumor with a negative margin and mobility of the pancreas to facilitate subsequent anastomosis. Frozen section confirmed negative margins. An invaginating three-layer Roux-en-Y pancreaticojejunostomy was created using an outer layer of interrupted silk, an inner layer of running Maxon, and interrupted sutures approximating the pancreatic duct and jejunal mucosa. This technique was chosen because of the thickness of the pancreas and the small diameter of the pancreatic duct. A stent was placed into the pancreatic duct and externalized through a separate opening in the jejunum.. A Chromic stitch was placed between the pancreatic duct and jejunum and then tied to the stent. Jackson-Pratt drains were placed next to the anastomosis and the pancreatic staple line. The patient was discharged on the sixth postoperative day and had no complications. Pathology revealed a pancreatic lipoma with negative margins. The drains were removed prior to discharge after confirming low amylase content in the drainage fluid. The pancreatic stent was removed after 6 weeks. The patient is normogylcemic with no symptoms of pancreatic insufficiency at one year follow-up.