This videotape discusses the management of a patient with malignant melanoma from the point of primary treatment throughout a clinical course that includes the development of metastasis and a second primary pulmonary neoplasm. The format includes discussion of the pathology of melanoma, the role of lymphadenectomy in primary treatment and the management of melanoma as a chronic disease. The method of presentation incorporates questions and answers, thereby allowing the viewer to participate in formulating the definitive course of therapy for the patient.