Minimally-invasive video-assisted thyroidectomy (MIVAT) is safe and effective in the hands of experienced surgeons when proper technique and patient selection are used. This video documents thyroid nodule evaluation, paient selection, surgical technique, and outcomes for MIVAT at a single center. The patient in this video underwent MIVAT for an asymptomatic follicular neoplasm. Between 2002 and 2004, 22 patients underwent MIVAT and 26 conventional thyroidectomy patients served as matched controls. Operative time, analgesic requirements, and incision length were retrospectively evaluated. Mean operative time was 102 min (MIVAT) vs 86 min (open) [p<0.05]. Mean incision length was 2.3cm in the MIVAT group. Conventional thyroidectomy was performed through a 4-5 cm incision. Average narcotic used within the first 24 hours was not significantly different. One patient in each group experienced transient hoarseness. There were no cases of permanent hypoparathyroidism or recurrent laryngeal nerve injury in either group. The patient in this video had an uneventful recovery after same-day discharge. In the hands of experienced surgeons and with proper patient selection, MIVAT is feasible, safe, and can lead to successful same-day discharge.