The tape outlines the indications, precautions, and technique developed and practiced in this institution for the performance of laparoscopic cholecystectomy for symptomatic gallstone disease. The procedure entails a two-handed scissor dissection of the cystic pedicle, followed by laparoscopic cholangiography, Rowder knot ligation or clipping of the cystic duct and artery, mobilization of the detached gallbladder from the liver, and extraction of the organ. In our experience the procedure is applicable to 80% of patients with symptomatic disease. We consider the laparoscopic approach to be contraindicated in patients with jaundice, acute cholecystitic pancreatitis, and the morbidly obese.