Multimedia • CME • Publishing • Courses

Book Offers Poignant Overview of the Evolution of Managing Peritoneal Surface Malignancy

What has Paul H. Sugarbaker, MD excited about Chapter 8 in Cytoreductive Surgery and Perioperative Chemotherapy for Peritoneal Surface Malignancy?

Management of Unusual Abdominal and Pelvic Neoplasms with Peritoneal Dissemination is one of Sugarbaker's favorites because it offers a poignant overview of the evolution of managing peritoneal surface malignancy. Persistent data analysis led to the creation of prognostic indicators that are now used for the selection of patients best-suited to the treatment techniques and positive outcomes.

This chapter offers 10 case reports outlining unusual abdominal and pelvic neoplasms that satisfy the criteria for long-term benefit as a result of treatment using a combination of cytoreductive surgery and perioperative chemotherapy.

Table: Quantitative prognostic indicators in patients with peritoneal malignancy from adenocarcinoid of appendiceal origin

Quantitative Prognostic Indicator # Patients Survival (months)* P Value**
Peritoneal cancer index
< 10
11 to 20
> 20
4
8
10
61.5 (23.3 to 95.1) (10.2, 110.3)
21.0 (7.3 to 31.4) (13.2, 26.3)
6.1 (3.2 to 78.1) (-0.6, 31.7)
0.008
Completeness of cytoreduction
CC-0 to CC-1
CC-2
CC-3
6
7
9
28.5 (13.4 to 95.1) (9.2, 78.5)
18.1 (7.3 to 78.1) (2.8, 47.2)
5.9 (3.2 to 48.4) (1.7, 24.2)
0.007
Prior surgical score
PSS-0 to PSS-1
PSS-2
PSS-3
4
7
11
9.5 (6.0 to 78.1) (-29.4, 81.4)
26.2 (16.4 to 75.3) (15.6, 53.5)
11.3 (3.2 to 95.1) (1.4, 36.6)
0.063
* Values are median (range) (95% confidence interval). ** Fisher's exact test

Paul H. Sugarbaker, MD, FACS, FRCS, is Section Director of the Program in Peritoneal Surface Malignancy at MedStar Washington Hospital Center and editor of Cytoreductive Surgery and Perioperative Chemotherapy for Peritoneal Surface Malignancy. This educational text for surgical and medical oncologists illustrates the rationale, treatment, and results of treatment of peritoneal metastases, peritoneal mesothelioma and sarcomatosis.

The book was introduced at the 8th Biannual Meeting of the Peritoneal Surface Oncology Group in Berlin in 2012. The book, along with a DVD set that includes surgical video with discussion by the author, are available from Ciné-Med, Inc.